Cryo-EM for Biologics. Decision-ready results, fast.

We answer the specific structural and morphological questions delivering decision-ready results at the speed development timelines demand.

ATEM is a strategic partner of the leading global CRO, Charles River.

What we offer

Services

Unlock the fundamentals of your protein. We tackle targets that are difficult to crystalize – including large assemblies or membrane proteins.

Lipid Nanoparticle Characterization

Our AI-powered solutions offer unprecedented quantitative data into the morphology of lipid nanoparticles. Cryo-EM offers observable results, something impossible with indirect methods like Dynamic Light Scattering (DLS). This combination enables robust formulation and forced degradation studies.

Cryo-EM Services

High-throughput 3D Epitope Mapping

Benefit from our unique, high-throughput cryo-EM platform, and discern challenging epitopes in 3D. With the possibilities of cryo-EM, you can screen several FAB/mAbs in complex with your target to visualize conformations, contacting residues, and binding locations.

Cryo-EM Services

3D Structure Determination

We provide control over the cryo-EM 3D structure determination process. With our cutting-edge cryo-EM facility, computational resources, and 50+ years of collective expertise, we optimize and de-risk project budget. Our unique biochemical sample optimization assays enhance project success rates.

Cryo-EM Services

Adeno Associated Viral Vector Characterization

Cryo-EM revolutionizes AAV characterization in gene therapy R&D, offering precise analysis of critical quality attributes. It enables unparalleled identification of full, empty, and intermediate AAV particles across various serotypes, enhancing quality assurance and therapeutic efficacy.

Cryo-EM Services

GMP TEM Viral Particle
Characterization

Why ATEM

The Answer You Need, When Your Program Demands IT

ATEM is a specialist cryo-EM CRO working exclusively in biologics, LNPs, AAV vectors & antibody programs.

Unlike generalist providers, we deliver decision-ready answers to the specific question blocking your next developtment milestones.

Why teams choose ATEM:

Fast & Affordable

Our workflows are engineered around the client’s program timeline. Fit-for-purpose scoping means clients are not paying for analysis beyond what their question requires.

Precise Structural Insights

We work exclusively in biologics. That exclusivity is not a limitation, it is the source of the precision that generalist providers cannot match.

Decision-Ready Output

Every engagement ends with a panel-ready, decision-ready answer to the specific question your discovery campaign brought.

Regulatory & Scientific Credibility

Our team of experts is the backbone of our GMP-certified operations, which enables us to deliver outputs that withstand both regulatory scrutiny and scientific peer review.