Unlock the fundamentals of your protein. We tackle targets that are difficult to crystallize – including large assemblies or membrane proteins. Whether buried in a binding pocket or multiple proteins of a larger complex, use our cryo-EM capabilities to screen multiple ligands. Structural determination has never been easier.
Patent applications? Rational candidate selection? We create high-resolution 3D epitope maps that feature your target complex with a palette of mAb/Fab candidates.
In contrast to being forced into a rigid crystal lattice, cryo-EM samples are flash-frozen in a myriad of naturally occurring structural states. With ATEM’s increasingly powerful data processing, we can now deliver distinct dynamic states of proteins at high resolution.