Viral particle
analysis

VIRAL PARTICLE ANALYSIS FOR QUALITY CONTROL

We offer solutions in viral particle analysis for release testing. Transmission electron microscopy (TEM) opens up unique opportunities to investigate cell morphology and rule out contaminants. Cellular samples are sliced into ultra-thin sections, allowing visibility of entire cell morphology, organelles, viral particles, and other contaminants. Get a full overview of your research and production quality under secure GMP practice that leverages our TEM expertise together with excellent, long-lasting experience from Charles River.

See your production quality in a new light. While standard methods such as RT-PCR can highlight specific viruses, TEM shows the entirety of the sample and acts as a safety net to rule out unwanted contamination and determine cell morphology. Visual sample characterization highlights any unexpected properties and lets no contaminants go through. 

Visually identify and quantify

Key application areas

Application examples

AT THE FOREFRONT OF
INDUSTRIAL CRYO-EM TECHNOLOGY

LET'S DISCUSS YOUR PROJECT

 

1. Bulk harvest

We offer screening for viral particles in crude cell material, such as from fermentation. All viral particles are labeled and quantified for the final report, together with exemplary images.

 

2. Cell line characterization

We identify contamination and distinguish viral particles from cellular tissue.

Viral particle analysis
method overview

Cell preparation

01

TEM preparation

02

Data collection and processing

03

Results

04

Sample requirements

We prepare everything else! We receive your sample – optimize and test it, before returning the data in a personalized way that suits you.

Sample amounts

Get insight into detailed parameters with sample amounts of 20 ml.

Turnaround times

Results in 20 days or faster.

Results

Receive an extensive report highlighting cell morphology and viral particles/contaminants.